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Week 4 of the NFL season is marked by a surge in high-profile injuries, with star players like Justin Jefferson, Aaron Donald, and Travis Etienne ruled out. Teams are adjusting lineups and strategies on short notice, while off-field issues, such as Jed York's suspension, add to the league's challenges. The Cowboys' defensive rebuild through trades highlights a broader trend of teams pivoting to address immediate gaps. These developments may indicate a growing strain on rosters and front offices alike.